2. Metabolic Enzyme/Protease
  3. PCSK9
  4. Bococizumab

Bococizumab  (Synonyms: 伯考赛珠单抗; PF-04950615; RN316)

目录号: HY-P99187 纯度: 99.80%
COA

摩尔计算器

Bococizumab (PF-04950615) 是一种抗-人 PCSK9 的抗体抑制剂，可降低低密度脂蛋白胆固醇 (LDL-C) 水平。Bococizumab 可用于高胆固醇血症的研究。

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CAS No. : 1407495-02-6

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规格 价格 是否有货 数量
1 mg ￥4200
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Customer Review

Bococizumab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Bococizumab (PF-04950615) is an anti-human PCSK9 inhibitory antibody that reduces LDL cholesterol levels. Bococizumab can be used in the research of hypercholesterolemia[1][2].

同型

Human IgG2 kappa
推荐同型对照抗体
种属

Humanized
IC50 & Target

PCSK9[1]
体内研究
(In Vivo)

Bococizumab (0-100 mg/kg, i.v.) decreases maternal and fetal cholesterol and does not affect rat embryo-fetal development[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Pregnant Sprague-Dawley (SD) rats[1]
Dosage: 0, 10, 30, and 100 mg/kg
Administration: Intravenous injection (i.v.)
Result: Decreased in fetal cholesterol levels.
Showed well tolerance and no effects on ovarian or uterine parameters.
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

伯考赛珠单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG2 kappa
纯度 & 产品资料

纯度: 99.80%

COA (264 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Bococizumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bococizumab1407495-02-6PF-04950615 RN316伯考赛珠单抗PF04950615PF 04950615RN316RN 316RN-316PCSK9Proprotein convertase subtilisin/kexin type 9HypercholesterolemiacholesterolembryofetalLDL-CInhibitorinhibitorinhibit

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